| San Jose (SJO) | 21:39 21:40 | onderweg vertraagd | Copa Airlines Iberia Air Europa KLM SA AVIANCA Turkish Airlines | CM 162 IB 1662 UX 2804 KL 3010 AV 6721 TK 9600 | 1 | 103 |
| Bogota (BOG) | 21:40 | onderweg | SA AVIANCA | AV57 | 1 | |
| São Paulo (GRU) | 21:40 21:50 | onderweg vertraagd | Copa Airlines Emirates Gol Azul Turkish Airlines | CM 759 EK 4763 G3 6907 AD 7571 TK 9602 | 2 | 211 |
| Lima (LIM) | 21:40 | onderweg | Copa Airlines KLM Turkish Airlines | CM 337 KL 3014 TK 9527 | 2 | 207 |
| Cali (CLO) | 21:41 21:47 | onderweg vertraagd | Copa Airlines United Airlines KLM Turkish Airlines | CM 323 UA 7098 KL 8887 TK 9614 | 1 | 107 |
| Cartagena (CTG) | 21:44 21:54 | onderweg vertraagd | Copa Airlines KLM | CM 202 KL 8877 | 1 | 144 |
| Havana (HAV) | 21:50 | onderweg | Copa Airlines Iberia Air France KLM | CM 217 IB 1761 AF 5536 KL 8871 | 2 | 201 |
| Montevideo (MVD) | 22:11 | geplande | Copa Airlines KLM Air France United Airlines Turkish Airlines | CM 368 KL 3054 AF 5526 UA 7143 TK 9231 | 2 | 215 |
| Ciudad Trujillo (SDQ) | 22:13 | geplande | Copa Airlines KLM Air France Turkish Airlines | CM 107 KL 3056 AF 5539 TK 9551 | 1 | 121 |
| Barranquilla (BAQ) | 22:20 22:30 | geplande vertraagd | Copa Airlines United Airlines KLM Turkish Airlines | CM 826 UA 7058 KL 8869 TK 9622 | 2 | 221 |
| Bogota (BOG) | 22:20 22:30 | geplande vertraagd | Copa Airlines | CM886 | | |
| San Salvador (SAL) | 22:28 22:38 | geplande vertraagd | Copa Airlines Iberia KLM Air France Turkish Airlines | CM 878 IB 1684 KL 3002 AF 5357 TK 9559 | 1 | 106 |
| Quito (UIO) | 22:30 | geplande | Copa Airlines KLM Air France Turkish Airlines | CM 211 KL 3037 AF 5531 TK 9434 | 1 | 125 |
| Bogota (BOG) | 22:31 | geplande | Copa Airlines | CM430 | 2 | 219 |
| Higuey (PUJ) | 22:32 | geplande | Copa Airlines Air France KLM Turkish Airlines | CM 728 AF 5359 KL 8889 TK 9556 | 1 | 123 |
| Comayagua (XPL) | 22:33 | geplande | Copa Airlines Iberia Air Europa KLM Air France | CM 385 IB 1687 UX 2811 KL 3059 AF 4511 | 1 | 109 |
| Buenos Aires (EZE) | 22:37 | geplande | Copa Airlines | CM367 | 2 | 209 |
| Cancun (CUN) | 22:44 22:54 | geplande vertraagd | Copa Airlines | CM356 | 1 | 102 |
| Rio de Janeiro (GIG) | 22:45 | geplande | Copa Airlines Emirates Gol Azul | CM 216 EK 4757 G3 6915 AD 7557 | 2 | 220 |
| Bogota (BOG) | 03:40 | geplande | SA AVIANCA | AV41 | 1 | |
| Miami (MIA) | 04:02 04:12 | geplande vertraagd | Cargojet | W81002 | | |